Intestinal adaptation to diabetes. Altered Na-dependent nutrient absorption in streptozocin-treated chronically diabetic rats.

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Intestinal Adaptation to Diabetes Nutrient Chronically Diabetic Rats

To examine the pattern and mechanism of enhanced intestinal nutrient absorption in diabetes, we measured intestinal transport of 3-0-methylglucose (30MG), I-alanine (ALA), and SO4 in male Lewis rats made diabetic with streptozocin. Diabetes enhanced 30MG absorption fivefold in ileum and threefold in jejunum; ALA absorption increased twofold in ileum but not at all in jejunum; ileal S04 transpor...

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Intestinal Adaptation to Diabetes Nutrient Chronically Diabetic Rats Richard

To examine the pattern and mechanism of enhanced intestinal nutrient absorption in diabetes, we measured intestinal transport of 3-0-methylglucose (30MG), I-alanine (ALA), and SO4 in male Lewis rats made diabetic with streptozocin. Diabetes enhanced 30MG absorption fivefold in ileum and threefold in jejunum; ALA absorption increased twofold in ileum but not at all in jejunum; ileal S04 transpor...

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INTESTINAL ZINC ABSORPTION IN DESFERROXAMINE-TREATED RATS

Desferroxamine (Desferal) is used tochelate iron in thalassemia, a disease of very high prevalence in various parts of lran. We have investigated intestinal zinc absorption in Desferal-treated rats which, in pilot experiments, showed low serum levels of both iron and zinc. Intraperitoneal administration of ten 0.5 g doses of Desferal (one injection every other day) to male rats produced sev...

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intestinal zinc absorption in desferroxamine-treated rats

desferroxamine (desferal) is used tochelate iron in thalassemia, a disease of very high prevalence in various parts of lran. we have investigated intestinal zinc absorption in desferal-treated rats which, in pilot experiments, showed low serum levels of both iron and zinc. intraperitoneal administration of ten 0.5 g doses of desferal (one injection every other day) to male rats produced severe ...

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Intestinal adaptation in diabetes: amino acid absorption.

LAL, DHEERAJ, AND HAROLD P. SCHEDL. Intestinal adaptation in diabetes: amino acid absorption. Am. J. Physiol. 227(4): 827-831. 1974.-Since the diabetic rat shows adaptations in intestinal hexose absorption, we studied amino acid absorption 5 and 12 days after induction of diabetes with alloxan or streptozotocin. We perfused the entire small intestine intraluminally with 5 mM amino acid solution...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1987

ISSN: 0021-9738

DOI: 10.1172/jci112991